At a Glance
The pharmacology program offers a variety of different options for you to gain experience and knowledge through a degree path that best fits your career goals:
The Pharmacology Ph.D program at the University of Minnesota is designed to provide a solid understanding of basic pharmacology and to prepare our graduates to pursue careers as independent scientists and pharmacologists.
Our M.S. program is designed to provide career-focused individuals with a highly individualized program of study. Graduates of this program will find that they have built a strong platform to reach towards their future goals.
The Pharmacology Graduate Program participates in both the M.D./Ph.D. program and the J.D./Ph.D. Program provided by the university. Both of these joint degree programs allow motivated students to earn a dual degree in less time than it would normally take.
Research focus areas:
- Cancer and infectious diseases: Researching the fundamental aspects of how cancer cells proliferate and metastasize, how inflammatory and immunological responses are modulated during infection and what the structural basis of virus host cell interaction are.
- Neuropharmacology and neurodegeneration: Innovative research directed at mechanisms of neuronal function under normal conditions and in neurodegenerative diseases such as Alzheimer's disease.
- Cell signaling: Investigating a spectrum of cellular and molecular processes regulating the mammalian genome in healthy cells, as well as how they may go wrong in diseased conditions.
- Drug addiction and toxicology: Using multidisciplinary approaches involving cell and animal models to address drug addiction’s key questions: why some individuals transit from casual drug use to addiction, and why drug relapse is so common.
Studying mechanisms of DNA repair and genome instability in mammalian somatic cells.
Studying the molecular basis of the cytotoxicity of topoisomerase-targeted anticancer and antimicrobial drugs.
Studying the neuropharmacological mechanisms of addiction to nicotine and alcohol.
Studying the structural biology of human diseases including virus infections, cancer, and abnormal blood pressure.
Studying drugs that modulate neurotoxicity and neuronal signaling processes.
Studying the molecular and cellular mechanisms underlying excitability in the brain and heart.
Studying RNA editing in trypanosomes and mammalian iron homeostasis.
Exploiting tissue homeostatic mechanisms to target tumor initiation and dormancy.
Studying the neurochemical mechanisms of opioids--major pain killers with addictive potential.
Studying chromosome stability, telomerase structure and function, and gene amplification.
Studying the regulation of calcium mobilization by cyclic ADP-ribose and other nucleotides.
Studying the regulation and function of cholesterol in brain, its role in neurodegenerative diseases and neuroprotective mechanisms of cholesterol lowering drugs.
Studying the regulation of membrane-proximal signaling in hematopoietic cells.
Studying the role of proteases as therapeutic targets and the use of antibodies as tumor imaging and anti-tumor agents.
Studying allosteric regulation in cell signaling and cancer - Developing allosteric kinase inhibitors.
Studying the spatial and temporal dynamics of intracellular Ca2+ signals.
Studying growth factor and hormone signaling in cancer.
Studying the regulatory pathways and mechanisms for adipocyte and neuronal differentiation, and in metabolic diseases.